Molecular and Cellular Mechanisms of Action of Cannabidiol

Cannabidiol (CBD) is the primary non-psychoactive chemical from Cannabis Sativa, a plant used for centuries both recreational and medicinal purposes. CBD lacks psychotropic effects of Δ9-tetrahydrocannabinol (Δ9-THC) has shown great therapeutic potential. exerts wide spectrum at molecular, cellular, organ level, affecting inflammation, oxidative damage, cell survival, pain, vasodilation, excitability, among others, modifying many physiological pathophysiological processes. There evidence that may be effective in treating several human disorders, like anxiety, chronic psychiatric pathologies, cardiovascular diseases, even cancer. Multiple cellular pre-clinical studies using animal models disease trials have an overall safe profile. In this review article, we summarize pharmacokinetics data, putative mechanisms action CBD, reported to give comprehensive list findings major attributed compound.